TOP1M Polyclonal Antibody, 100ul Filtration The beta-1

The beta-1

They are also characterized by a catalytic triad composed of a histidine

depending on stage of neuronal maturation and neuron type

Overexpression of this gene has been implicated in tumorigenesis

Belongs to the protein phosphatase inhibitor 1 family

TOP1M Polyclonal Antibody, 100ul Filtration The beta-1This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.