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Heme induced oxidative stress attenuates sirtuin1 and enhances adipogenesis in mesenchymal stem cells and mouse pre-adipocytes

L-carnitine effectively reversed these effects by ameliorating p65 NF-B expression and reducing levels of inflammatory cytokines (IL-1 and TNF-)

IL-33 Stabilized -catenin to facilitate its function as a transcription factor, promoting the expression of CCN4 and Fra-1 In addition to changes in protein expression, we observed that -catenin Ser552 was primarily located in the nucleus, whereas -catenin Ser675 was predominantly cytoplasmic (Fig