Ro-3306 pafenac 2414591-05-0

2414591-05-0

SJ000291942 induces p-SMAD1/5/8 maximally at 1hr of treatment

(Formulated in hydrochloric acid (0

QAW039 was also a potent inhibitor of PGD2-induced cytokine release in human Th2 cells

841290-80-0 (Tamatinib free base)

Ro-3306 pafenac 2414591-05-0RO 3306 is a CDK1 inhibitor with potential anticancer activity. Treatment of growing AML cells with RO 3306 induced G2 M phase cell cycle arrest and apoptosis in a dose and time dependent manner. RO 3306 downregulated expression of the antiapoptotic proteins Bcl 2 and survivin and blocked p53 mediated induction of p21 and MDM2. RO 3306 actively enhances downstream p53 signaling to promote apoptosis. Product information CAS Number: 872573 93 8