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This initiates a cycle of inflammation that persists until the underlying insult is resolved (Adamczak et al., 2014

5 Limitations of current estrogen-based therapies Traditional systemic estrogen replacement therapies, with doses varying from 150 to 2000 g/day are effective for treating menopausal symptoms such as hot flashes and vaginal dryness and also have beneficial effects on bone loss, and skin appearance and repair

It exhibits dynamic composition changes to support infant health

While many studies show that chronic (several day) exposure during development induces morphological, behavioral, and genomic changes, very few have examined the effect of a brief exposure and/or the impact of a recovery/washout period on assessed outcomes

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