SC-79 - CAS# 305834-79-1 Catalog No.:M6552-2 209783-80-2

209783-80-2

Major Depressive Disorder and Kappa Opioid Receptor Antagonists

Smiles: CC1(C)C=CC2=CC(CCN3C4=CC=CC=C4C4=CC=CC=C34)=CC(C=O)=C2O1

Chemical Name: N-(furan-2-yl(8-hydroxyquinolin-7-yl)methyl)isobutyramide

Formula: C9H16Br2N5O4P

SC-79 - CAS# 305834-79-1 Catalog No.:M6552-2 209783-80-2SC 79, CAS No. 305834 79 1, is an activator of Akt that blocks its membrane translocation while allowing its phosphorylation, in the cytosol, by upstream kinases. SC 79 is a potential treatment for alcohol induced osteonecrosis of the femoral head. SC 79 injections inhibited alcohol induced osteonecrosis. Alcohol induced ONFH is associated with suppression of p Akt Ser473 in the Akt GSK3 catenin signaling pathway in bone mesenchymal stem cells.