EBE-A22 60181 Formula: C4H6N4O3S2

Formula: C4H6N4O3S2

increased blood hemoglobin and hematocrit

Chemical Name: (4E)-2-(2-phenylethenyl)-4-[(pyridin-3-yl)methylidene]-4

Chemical Name: 2-[1-(aminomethyl)cyclohexyl]acetic acid hydrochloride

InChiKey: IZEKFCXSFNUWAM-UHFFFAOYSA-N

EBE-A22 60181 Formula: C4H6N4O3S2EBE A22 is a derivative of PD 153035. EBE A22, has no effect on EGF R TK but maintains a high cytotoxic profile. EBE A22 binds to DNA and behave as typical intercalating agents. EBE A22 unwinds supercoiled plasmid, stabilizes duplex DNA against heat denaturation, and produces negative CD and ELD signals, as expected for an intercalating agent. EBE A22, but not PD153035, interacts preferentially with GC rich sequences and discriminates against