Ranolazine dihydrochloride - CAS# 95635-56-6 xidant with anticancer activities PMID: 29926593

PMID: 29926593

CC1(C)C2C3=CC=CC=C3C=CC=2[N+](CCCCS([O-])(=O)=O)=C1/C=C/C=C/C=C/C=C1/N(CCCCS([O-])(=O)=O)C2=CC=C3C=CC=CC3=C2C/1(C)C

Mitochondrial metabolism of pyruvate is essential for regulating glucose-stimulated insulin secretion

Formula: C16H20Cl2FN3O2

6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3

Ranolazine dihydrochloride - CAS# 95635-56-6 xidant with anticancer activities PMID: 29926593Ranolazine is an anti ischemic compound, which inhibits late sodium current that results in a reduction of Na+ dependent Ca2+ overload. Studies indicate that ATP production is shifted towards glucose oxidation by Ranolazine. This is due to the fact that more oxygen is required to phosphorylate the same amount of ATP during fatty acid oxidation than carbohydrate oxidation. These studies indicate that Ranolazine also inhibits oxygen consumption and