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Results showed a significant reduction in risk for RA in patients treated with GLP-1 receptor agonists (HR = 0.87

4.2.1.2 Nephrotoxic mechanisms of indoxyl sulfate (IS) Indoxyl sulfate (IS) is one of the most representative protein-bound uremic toxins, formed from indole produced by gut microbiota metabolism of tryptophan through hepatic sulfation