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BYL-719 - CAS# 1217486-61-7 41795 9-dioxo-3-[(pyrazin-2-yl)methyl]-1H

BYL-719 - CAS# 1217486-61-7 41795 9-dioxo-3-[(pyrazin-2-yl)methyl]-1H

Name: BYL-719 - CAS# 1217486-61-7 41795 9-dioxo-3-[(pyrazin-2-yl)methyl]-1H
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SKU: 47048925660
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SKU: 47048925660

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BYL-719 - CAS# 1217486-61-7 41795 9-dioxo-3-[(pyrazin-2-yl)methyl]-1HAlpelisib, also known as BLY719, is an orally bioavailable phosphatidylinositol 3 kinase (PI3K) inhibitor with potential antineoplastic activity. Alpelisib is equipotent against both wild type and several mutant isoforms (IC50s = 4. 0 4. 8 nM). eCollection 2020. Navitoclax combined with Alpelisib effectively inhibits Merkel cell carcinoma cell growth in vitro. Alpelisib Plus Letrozole Shows Promise After CDK 4 6 Inhibitor Therapy in PIK3CA Mutated HR+

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Description

9-dioxo-3-[(pyrazin-2-yl)methyl]-1H

J Pharm Belg

(2014) Nat Chem Biol

off-tumor toxicities of chimeric antigen receptor T cells

Smiles: O=C1C2=CC=CC=C2N(CC2C=CC(Br)=CC=2)C1=O

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