LAX1 Polyclonal Antibody, 50ul Multiplex Immunoassays Mutations in this gene may

Mutations in this gene may be associated with susceptibility to coronary artery disease

It has higher identity to E2F4 than to other family members

It may play an important role in hemopoietic differentiation

One of the transcripts produced from this locus

This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes

LAX1 Polyclonal Antibody, 50ul Multiplex Immunoassays Mutations in this gene mayNegatively regulates TCR (T cell antigen receptor) mediated signaling in T cells and BCR (B cell antigen receptor) mediated signaling in B cells.,induction: Up regulated in T cells following TCR engagement.,PTM: Phosphorylated on tyrosines by Syk, Lck or ZAP70 upon TCR or BCR activation; which leads to the recruitment of GRB2, PIK3R1 and GRAP2.,subunit: When phosphorylated, interacts with GRB2, PIK3R1 and GRAP2.,tissue specificity: Expressed in