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[12] Gastric acid-suppressing agents (proton-pump inhibitors and H-receptor antagonists) diminish dietary B12 liberation from protein complexes, a pharmacodynamic interaction that can exacerbate underlying deficiency

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Perhaps this indicates that in the early stages of ME/CFS, the immune system actively attempts to target the infectious burden (193)

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The other advantage of glycine is it works on phase 2 liver detoxification, which is amino acid conjugation