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Tombes, R

When injected weekly, it activates GLP-1 receptors in your hypothalamus and gut, triggering feelings of satiety and reducing food cravingsprocesses that occur completely separate from physical activity

It changes how the body manages energy, focusing on targeting metabolically active fat rather than simply cutting back on calories

The key distinction is the addition of glucagon receptor (GCGR) agonism

Alongside GLP-1RAs, newly emerging peptide polyagonists (i.e., synthetic molecules that combine the amino acid sequences of more than one peptide, thus having the ability to bind more than one receptor) are now being investigated in NAFLD with high expectations