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doi:10.2337/db14-1577 259

If side effects occur, your healthcare provider might extend this phase by an additional four weeks to ensure comfort and safety

This anatomical alteration likely resulted in reduced GIP secretion, while GLP-1 secretion may have remained intact, given that hypoglycemic episodes occurred several hours after ingestion of small liquid meals, suggesting an exaggerated insulin response possibly driven by GLP-1, unopposed by glucagon due to insufficient GIP activity

The physiologic significance of the hormone effect was confirmed using in vivo models such as insulin-deficient diabetic or adrenalectomized rats

Trulicity is a synthetic GLP-1 receptor agonist (RA)