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AZD9496 - CAS# 1639042-08-2 Catalog No.:M7101-2 Ferrostatin-1 was characterized to prevent

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AZD9496 - CAS# 1639042-08-2 Catalog No.:M7101-2 Ferrostatin-1 was characterized to preventAZD9496, CAS No. 1639042 08 2, is a potent and orally bioavailable selective estrogen receptor downregulator and antagonist. AZD9496 can induce ER degradation in breast cancer cell lines at picomolar concentrations. AZD9496 is curently under clinical trials. AZD9496 may be useful for the treatment of ER+ breast cancer. Product information CAS Number: 1639042 08 2 Molecular Weight: 442. 47 Formula: C25H25F3N2O2 Synonym: AZD9496 AZD 9496 AZD 9496

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Description

Ferrostatin-1 was characterized to prevent erastin-induced accumulation of cytosolic and lipid ROS

It does not inhibit other DUBs or other families of cysteine proteases tested (EC50 > 100 mM)

35 days) addition from day 0 significantly increases myocardial differentiation and results in a significantly increased percentage of CBs with beating cardiomyocytes

287±16 mm3

Epub 2012 Jun 25

AZD9496 - CAS# 1639042-08-2 Catalog No.:M7101-2 Ferrostatin-1 was characterized to preventAZD9496, CAS No. 1639042 08 2, is a potent and orally bioavailable selective estrogen receptor downregulator and antagonist. AZD9496 can induce ER degradation in breast cancer cell lines at picomolar concentrations. AZD9496 is curently under clinical trials. AZD9496 may be useful for the treatment of ER+ breast cancer. Product information CAS Number: 1639042 08 2 Molecular Weight: 442. 47 Formula: C25H25F3N2O2 Synonym: AZD9496 AZD 9496 AZD 9496

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