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They can help patients improve and protect their health, so its worth having a conversation with your provider if you think you could benefit

Potential direct benefits suggested by preclinical research include reduction of neuroinflammation, enhancement of neuronal insulin signaling, promotion of synaptic plasticity, and possible reduction in pathological protein accumulation

However, the potential for delaying or preventing the progression of T2DM in patients treated with GIP and GLP-1 remains uncertain, as there is currently no definitive evidence from human studies demonstrating that enhanced incretin activity directly affects -cell mass or alters the progressive loss of insulin secretory capacity in humans

GLP-1s are FDA-approved as an adjunct to nutrition and lifestyle therapy

Predictors of weight loss in adults with topiramate-treated epilepsy