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Biopharmaceutics & Drug Disposition, 21(1), 15-22

Participants with obesity and a clinical and radiologic diagnosis of moderate knee osteoarthritis with at least moderate pain were randomly assigned, in a 2:1 ratio, to receive once-weekly subcutaneous semaglutide (2.4 mg) or placebo, in addition to counselling on physical activity and a reduced-calorie diet

Interestingly, even normal metabolic processes, like making energy (ATP), generate oxidative byproducts that deplete glutathione stores

Your surgeon can coordinate with your primary care team to support your safety and aesthetic goals