R-1479 Catalog No.:M10813-10 3)-D-glucan

3)-D-glucan

the JAK2V617F gain-of-function mutation involves a valine-to-phenylalanine modification at position 617

Chemical Name: 5-chloro-N-[4-methoxy-3-(piperazin-1-yl)phenyl]-3-methyl-1-benzothiophene-2-sulfonamide hydrochloride

the presence ofmethylproamine decreased the amount of lower molecular weight DNA entering the gel as shown by the pulsed field gel electrophoresis assay

PIK-75 Hydrochloride

R-1479 Catalog No.:M10813-10 3)-D-glucanR 1479, also known as 4' azidocytidine, is a potent inhibitor of NS5B dependent RNA synthesis and hepatitis C virus replication in cell culture. R 1479 is a specific inhibitor of HCV replication in the HCV subgenomic replicon system (IC(50) = 1. 28 microM). The corresponding 5' triphosphate derivative (R1479 TP) is a potent inhibitor of native HCV replicase isolated from replicon cells and of recombinant HCV polymerase (NS5B) mediated RNA synthesis