Co-1686 - CAS# 1374640-70-6 Catalog No.:M111-2S MK-1775 can regresse H3K36me3-deficient tumor

MK-1775 can regresse H3K36me3-deficient tumor xenografts too

and delay in tumor recurrence

MDA-MB-435

InChi: InChI=1S/C55H83N17O21S3/c1-20-33(69-46(72-44(20)58)25(12-31(57)76)64-13-24(56)45(59)82)50(86)71-35(41(26-14-61-19-65-26)91-54-43(39(80)37(78)29(15-73)90-54)92-53-40(81)42(93-55(60)88)38(79)30(16-74)89-53)51(87)66-22(3)36(77)21(2)47(83)70-34(23(4)75)49(85)63-10-8-32-67-28(18-94-32)52-68-27(17-95-52)48(84)62-9-7-11-96(5)6/h14

is a potent

Co-1686 - CAS# 1374640-70-6 Catalog No.:M111-2S MK-1775 can regresse H3K36me3-deficient tumorCO 1686, CAS No. 1374640 70 6, is an orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M, and the Ki values for EGFRL858R T790M and EGFRWT are 21. 5 nM and 303. 3 nM, respectively. Product information CAS Number: 1374640 70 6 Molecular Weight: 555. 55 Formula: C27H28F3N7O3 Synonym: Rociletinib AVL 301 Chemical Name: N (3 ((2 ((4 (4 acetylpiperazin 1 yl) 2 methoxyphenyl)amino) 5