RJR-2403 (oxalate) Size:Solid 2 mg JNK-IN-8 inhibits c-Jun phosphorylation in

JNK-IN-8 inhibits c-Jun phosphorylation in HeLa and A375 cells with EC50 of 486 nM and 338 nM

CAS Number: 912545-86-9

also known as ENA-713

InChi: InChI=1S/C44H51ClN10O9S/c1-28(2)65(61

It is suitable for super-resolution imaging including dSTORM

RJR-2403 (oxalate) Size:Solid 2 mg JNK-IN-8 inhibits c-Jun phosphorylation inMetanicotine, also known as RJR 2403 and TC 2403, is a neuronal nicotinic receptor agonist, showing high selectivity for the 42 subtype. Metanicotine has high affinity to rat brain cortex (Ki = 26 + 3 nM). Metanicotine is comparable to nicotine in activating rat thalamic synaptosomes (EC50 = 732 + 155 nM and Emax = 91 + 8% for RJR 2403; EC50 = 591 + 120 nM and Emax = 100 + 25% for nicotine) . Chronic administration of RJR 2403 in combination with low