Darapladib - CAS# 356057-34-6 205728 CID16020046 improves inflammation in models
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Darapladib - CAS# 356057-34-6 205728 CID16020046 improves inflammation in modelsDarapladib, also known as SB 480848, is a reversible lipoprotein associated phospholipase A2 (Lp PLA2) inhibitor with IC50 of 0. 25 nM, which is in Phase 3 trials. Recent studies showed that risk of major coronary events not reduced by darapladib therapy. In patients with stable coronary heart disease, darapladib did not significantly reduce the risk of the primary composite end point of cardiovascular death, myocardial infarction, or stroke. Product
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