HIF-1 beta Polyclonal Antibody, 100ul[BT-AP09890] Cell Culture Flasks NEIL1 is a member of

NEIL1 is a member of the Nei endonuclease VIII-like gene family which encodes DNA glycosylases

Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease)

Contains 1 SEC7 domain

Site-specific binding also suggests that 53BP1 and 53BP2 are involved in p53-mediated tumor suppression

and it associates maximally with the nucleotide-free states of these GTPases

HIF-1 beta Polyclonal Antibody, 100ul[BT-AP09890] Cell Culture Flasks NEIL1 is a member ofThis gene encodes a protein containing a basic helix loop helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co factor for transcriptional regulation by hypoxia inducible factor 1. Chromosomal translocation