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Mouse Dieptidyl Peptidase 4, DPP-4 ELISA Kit , 96T Molecular Biology The intestinal cell kinase localizes

SKU: 99921671301

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SEK185.49 SEK230.49

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Mouse Dieptidyl Peptidase 4, DPP-4 ELISA Kit , 96T Molecular Biology The intestinal cell kinase localizesCell surface glycoprotein receptor involved in the costimulatory signal essential for T cell receptor (TCR) mediated T cell activation. Acts as a positive regulator of T cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T cell proliferation and NF kappa B activation in a T cell receptor CD3 dependent manner. Its interaction with ADA also regulates lymphocyte epithelial cell adhesion. In

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Description

The intestinal cell kinase localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation

PubMed: 17932028

Component of the probable ECS(SPSB1) complex with the substrate recognition component SPSB1

Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3') (PubMed: 7903453

tissue specificity:Detected in whole brain

Mouse Dieptidyl Peptidase 4, DPP-4 ELISA Kit , 96T Molecular Biology The intestinal cell kinase localizesCell surface glycoprotein receptor involved in the costimulatory signal essential for T cell receptor (TCR) mediated T cell activation. Acts as a positive regulator of T cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T cell proliferation and NF kappa B activation in a T cell receptor CD3 dependent manner. Its interaction with ADA also regulates lymphocyte epithelial cell adhesion. In

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