Raf-1(Phospho Ser301) Polyclonal Antibody, 20ul Recombinant Ab Production Endophilin B2 is also a

Endophilin B2 is also a member of the Endophilin B subroup that is ubiquitously expressed but shows highest levels in brain

MAP3K2/MEKK2

heme A: farnesyltransferase cytochrome c oxidase assembly factor is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane

Alternate splicing of this gene results in several transcript variants encoding different isoforms

two (me2) or three (me3) methyl groups attached to the amine group of the lysine side chain

Raf-1(Phospho Ser301) Polyclonal Antibody, 20ul Recombinant Ab Production Endophilin B2 is also aThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.