MARE3 Polyclonal Antibody, 50ul Protein Analysis Studies of the related gene

Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons

The protein encoded by this gene is closely related to STAM| an adaptor protein involved in the downstream signaling of cytokine receptors| both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM)

and histone acetyltransferase domain

Neuromedin-U is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain

suggesting an important role for this protein in muscle tissue

MARE3 Polyclonal Antibody, 50ul Protein Analysis Studies of the related geneThe protein encoded by this gene is a member of the RP EB family of genes. The protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene.