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Smad3 Monoclonal Antibody(8B5), 100ul Primary Antibodies Mutations in SLC9A9 are associated

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Smad3 Monoclonal Antibody(8B5), 100ul Primary Antibodies Mutations in SLC9A9 are associatedThe protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor beta and is thought to play a role in the regulation of

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Description

Mutations in SLC9A9 are associated with autism susceptibility 16 and attention-deficit/hyperactivity disorder

The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions

which is secreted and found in the extracellular matrix

The protein is implicated in adipogenesis and erythropoiesis

The encoded protein mediates the termination of RNA polymerase I transcription by binding to Sal box terminator elements downstream of pre-rRNA coding regions

Smad3 Monoclonal Antibody(8B5), 100ul Primary Antibodies Mutations in SLC9A9 are associatedThe protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor beta and is thought to play a role in the regulation of

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