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HNF1 alpha(Phospho-Ser247) Rabbit Polyclonal Antibody, 100ul Sealing Film mutations in either gene may

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HNF1 alpha(Phospho-Ser247) Rabbit Polyclonal Antibody, 100ul Sealing Film mutations in either gene mayThe protein encoded by this gene is a transcription factor required for the expression of several liver specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5' GTTAATNATTAAC 3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different

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Description

mutations in either gene may contribute to these disorders

proteins interact with protein kinases and may serve as targets for activated GTPase

It is the major protein in sweat

Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes| dendritic cells| macrophages)

Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP

HNF1 alpha(Phospho-Ser247) Rabbit Polyclonal Antibody, 100ul Sealing Film mutations in either gene mayThe protein encoded by this gene is a transcription factor required for the expression of several liver specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5' GTTAATNATTAAC 3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different

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