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OPA1 Polyclonal Antibody, 100ul Human Genome Knockout Libraries disintegrin and epidermal growth factor-like

SKU: 96695685790

4.1
EUR123.75 EUR144.75

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OPA1 Polyclonal Antibody, 100ul Human Genome Knockout Libraries disintegrin and epidermal growth factor-likeThis gene product is a nuclear encoded mitochondrial protein with similarity to dynamin related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.

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Description

disintegrin and epidermal growth factor-like domains

TNFAIP2 (TNF alpha induced protein 2) was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells

TOP2A encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance

PAQR5 (Progestin And AdipoQ Receptor Family Member 5) is a Protein Coding gene

This gene encodes a member of the type-B carboxylesterase/lipase protein family

OPA1 Polyclonal Antibody, 100ul Human Genome Knockout Libraries disintegrin and epidermal growth factor-likeThis gene product is a nuclear encoded mitochondrial protein with similarity to dynamin related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.

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