Rap1GAP Polyclonal Antibody, 20ul Custom RNA Oligos Mutations in this gene are

Mutations in this gene are associated with gastrointestinal stromal tumors

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In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL)

particularly endothelial cells and mononuclear phagocytes

Mammalian mitochondrial ribosomal protein L 41 (39S ribosomal protein L41 mitochondrial) is encoded by nuclear gene MRPL41 and help in protein synthesis within the mitochondrion

Rap1GAP Polyclonal Antibody, 20ul Custom RNA Oligos Mutations in this gene areRAP1GAP encodes a type of GTPase activating protein (GAP) that down regulates the activity of the ras related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP bound form and an active GTP bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating