TPH2 Polyclonal Antibody, 20ul Liquid Storage Consumables Members of the CELF/BRUNOL protein

Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains

initiates survival pathways and cell proliferation

They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK

The encoded protein (apolipoprotein L2) is found in the cytoplasm

Three transcript variants encoding two different isoforms have been found for this gene

TPH2 Polyclonal Antibody, 20ul Liquid Storage Consumables Members of the CELF/BRUNOL proteinTPH2 encodes a member of the pterin dependent aromatic acid hydroxylase family. The tryptophan hydroxylase 2 catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.