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HoxD8 Polyclonal Antibody, 100ul Modified Oligos DEFA4 differs from other genes

SKU: 96338374539

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HoxD8 Polyclonal Antibody, 100ul Modified Oligos DEFA4 differs from other genesHOXD8 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. HOXD8 is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions

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Description

DEFA4 differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region

The amino terminus of calreticulin interacts with the DNA-binding domain of the glucocorticoid receptor and prevents the receptor from binding to its specific glucocorticoid response element

The three known members of this gene family are located in a cluster on chromosome 12

AZI1 is most highly expressed in spinal cord

Pipet Filter: Polyolefin (PO)

HoxD8 Polyclonal Antibody, 100ul Modified Oligos DEFA4 differs from other genesHOXD8 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. HOXD8 is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions

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