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Vav3 Polyclonal Antibody, 100ul ROS/Nitric Oxide Detection This protein is thought to

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Vav3 Polyclonal Antibody, 100ul ROS/Nitric Oxide Detection This protein is thought toVAV3 is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide free states of these GTPases. Alternatively spliced transcript variants encoding

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Description

This protein is thought to be be involved in multiple cellular processes| including maintenance of skin homeostasis| and suppression of invasiveness and metastasis

Defects in ITGA7 are associated with congenital myopathy

and requires vesicular acidification to bind lipid antigens

RPS6KA1 (ribosomal protein S6 kinase A1) encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases

SP100 (SP100 nuclear antigen) encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies

Vav3 Polyclonal Antibody, 100ul ROS/Nitric Oxide Detection This protein is thought toVAV3 is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide free states of these GTPases. Alternatively spliced transcript variants encoding

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