HDAC5 Polyclonal Antibody, 100ul Buffer Solutions High mobility group box 1

High mobility group box 1 plays a role in several cellular processes

proteins involved in various signal transduction pathways

Mutations in this gene may be associated with sporatic cases of neural tube defects

One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X

Overexpressed in a number of carcinomas

HDAC5 Polyclonal Antibody, 100ul Buffer Solutions High mobility group box 1Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 5 encoded by HDAC5 belongs to the class II histone deacetylase acuc apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with