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Phospho-ATR (S428) Polyclonal Antibody, 20ul Pipette Micro Tips which may be involved in

SKU: 95777345427

4.8
PLN97.20 PLN128.20

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Phospho-ATR (S428) Polyclonal Antibody, 20ul Pipette Micro Tips which may be involved inThe protein encoded by ATR (ATR serine threonine kinase) belongs the PI3 PI4 kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1,

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Description

which may be involved in regulatory processes important for development and cellular differentiation

an inherited bone marrow failure syndrome

many proteins are phosphorylated directly by MPF or indirectly by kinases activated by MPF

Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development

Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes

Phospho-ATR (S428) Polyclonal Antibody, 20ul Pipette Micro Tips which may be involved inThe protein encoded by ATR (ATR serine threonine kinase) belongs the PI3 PI4 kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1,

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