ACATN Polyclonal Antibody, 100ul Mammalian Expression CD6 (CD6 molecule) encodes a

CD6 (CD6 molecule) encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells

It is involved in a diverse array of cellular functions| including ER-to-Golgi transport| the centripetal movement of lysosomes and endosomes| spindle formation| cytokinesis| chromosome movement| nuclear positioning| and axonogenesis

Expressed in a variety of tissues with highest expression in liver

This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide

Several alternatively spliced transcript variants have been identified from this gene

ACATN Polyclonal Antibody, 100ul Mammalian Expression CD6 (CD6 molecule) encodes aThe protein encoded by this gene is required for the formation of O acetylated (Ac) gangliosides. The encoded protein is predicted to contain 6 to 10 transmembrane domains and a leucine zipper motif in transmembrane domain III. Defects in this gene have been reported to cause spastic paraplegia autosomal dominant type 42 (SPG42) in one Chinese family but not in similar patients of European descent. Two transcript variants encoding the same protein