Human Toll-like Receptor 7, TLR7 ELISA Kit , 96T In vitro Assessment The encoded protein is involved

The encoded protein is involved in docking and fusion events at the Golgi apparatus

May recognize and hydrolyze the peptide bond at the C-terminal Gly of ubiquitin

and it is thought to play an important role in mediating p53-dependent apoptosis

tissue specificity:Expression largely restricted to adipose tissue and spleen

|enzyme regulation:Specifically inhibited by the intercalating agent amsacrine

Human Toll-like Receptor 7, TLR7 ELISA Kit , 96T In vitro Assessment The encoded protein is involvedEndosomal receptor that plays a key role in innate and adaptive immunity (PubMed: 14976261, PubMed: 32433612). Controls host immune response against pathogens through recognition of uridine containing single strand RNAs (ssRNAs) of viral origin or guanosine analogs (PubMed: 31608988, PubMed: 27742543, PubMed: 12738885). Upon binding to agonists, undergoes dimerization that brings TIR domains from the two molecules into direct contact, leading to the