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TBC1D4 Polyclonal Antibody, 20ul Micro Centrifuge Tubes limiting DNA accessibility to the

SKU: 95312854443

4.2
USD97.20 USD118.20

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TBC1D4 Polyclonal Antibody, 20ul Micro Centrifuge Tubes limiting DNA accessibility to theTBC1D4 (TBC1 domain family member 4) is a member of the Tre 2 BUB2 CDC16 domain family. The protein encoded by TBC1D4 is a Rab GTPase activating protein, and contains two phopshotyrosine binding domains (PTB1 and PTB2), a calmodulin binding domain (CBD), a Rab GTPase domain, and multiple AKT phosphomotifs. This protein is thought to play an important role in glucose homeostasis by regulating the insulin dependent trafficking of the glucose transporter

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Description

limiting DNA accessibility to the cellular machineries which require DNA as a template

through association with Gi and Gq proteins

A nonconventional nuclear localization sequence (NLS) has been found for protein kinase cAMP-dependent type I regulatory subunit alpha which suggests a role in DNA replication via the protein serving as a nuclear transport protein for the second subunit of the Replication Factor C (RFC40)

regulates the kinase activity

COL2A1 encodes the alpha-1 chain of type II collagen

TBC1D4 Polyclonal Antibody, 20ul Micro Centrifuge Tubes limiting DNA accessibility to theTBC1D4 (TBC1 domain family member 4) is a member of the Tre 2 BUB2 CDC16 domain family. The protein encoded by TBC1D4 is a Rab GTPase activating protein, and contains two phopshotyrosine binding domains (PTB1 and PTB2), a calmodulin binding domain (CBD), a Rab GTPase domain, and multiple AKT phosphomotifs. This protein is thought to play an important role in glucose homeostasis by regulating the insulin dependent trafficking of the glucose transporter

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