LRP1B Polyclonal Antibody, 20ul Vacuum Filter Several alternatively spliced transcript variants|

Several alternatively spliced transcript variants| some of which encode distinct isoforms| have been identified

which translocates to the nucleus to function as a transcription factor

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Mutations in this gene have been associated with late-onset retinal degeneration

GO annotations related to this gene include receptor activity and carbohydrate binding

LRP1B Polyclonal Antibody, 20ul Vacuum Filter Several alternatively spliced transcript variants|This gene encodes a member of the low density lipoprotein (LDL) receptor family. These receptors play a wide variety of roles in normal cell function and development due to their interactions with multiple ligands. Disruption of this gene has been reported in several types of cancer.