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Tau(Phospho-Ser416) Rabbit Polyclonal Antibody, 50ul Bottles Act as a feedback negative

SKU: 94308365396

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Tau(Phospho-Ser416) Rabbit Polyclonal Antibody, 50ul Bottles Act as a feedback negativeThis gene encodes the microtubule associated protein tau (MAPT) whose transcript undergoes complex regulated alternative splicing giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease Pick's disease frontotemporal dementia cortico

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Description

Act as a feedback negative regulator of signaling by receptor tyrosine kinases

So far detected are isoform Alpha-6X1A| isoform Alpha-6X1B and isoform Alpha-6X1X2A (minor)

Also| this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase

and Liddle syndrome

Transcription initiation factor TFIID subunit 5 that coordinates these activities is transcription factor IID (TFIID)

Tau(Phospho-Ser416) Rabbit Polyclonal Antibody, 50ul Bottles Act as a feedback negativeThis gene encodes the microtubule associated protein tau (MAPT) whose transcript undergoes complex regulated alternative splicing giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease Pick's disease frontotemporal dementia cortico

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