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PROF1 Polyclonal Antibody, 20ul Polyclonal Antibody Preparation NF-kappa-B is a homo- or

SKU: 92835454946

4.6
SEK97.20 SEK121.20

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PROF1 Polyclonal Antibody, 20ul Polyclonal Antibody Preparation NF-kappa-B is a homo- orThis gene encodes a member of the profilin family of small actin binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1.

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Description

NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65| RELB| NFKB1/p105| NFKB1/p50| REL and NFKB2/p52

Mutations in this gene are associated with the disorders multiple endocrine neoplasia

and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors

Metalloproteinase inhibitor 4 encoded by this gene family are inhibitors of the matrix metalloproteinases

TP53I3 is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death

PROF1 Polyclonal Antibody, 20ul Polyclonal Antibody Preparation NF-kappa-B is a homo- orThis gene encodes a member of the profilin family of small actin binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1.

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