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GRK 3 Polyclonal Antibody, 100ul NGS Oligos The encoded protein facilitates translocation

SKU: 92381662576

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GRK 3 Polyclonal Antibody, 100ul NGS Oligos The encoded protein facilitates translocationThe beta adrenergic receptor kinase specifically phosphorylates the agonist occupied form of the beta adrenergic and related G protein coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.

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Description

The encoded protein facilitates translocation of a functional guanine nucleotide exchange factor (GEF) complex from the cytoplasm to the plasma membrane where ras-related C3 botulinum toxin substrate 1 is activated to promote lamellipodium formation and cell migration

Two transcript variants| only one of them protein-coding| have been found for this gene

AK1 encodes an adenylate kinase enzyme involved in energy metabolism and homeostasis of cellular adenine nucleotide ratios in different intracellular compartments

ZNF771 (Zinc Finger Protein 771) is a Protein Coding gene

Lactate dehydrogenase C catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis

GRK 3 Polyclonal Antibody, 100ul NGS Oligos The encoded protein facilitates translocationThe beta adrenergic receptor kinase specifically phosphorylates the agonist occupied form of the beta adrenergic and related G protein coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.

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