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It is a type I membrane protein

The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported

It is most active at neutral pH and is inhibited by active site-directed inhibitors of metallocarboxypeptidases

Polymorphisms in this gene are associated with systemic lupus erythematosus and allergic rhinitis

Oct-3/4 Polyclonal Antibody, 20ul[BT-AP06333] Cell Screening and Imaging Unleash your daring side andPOU5F1 encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of POU5F1 in adult tissues is associated with tumorigenesis. POU5F1 can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non AUG translation initiation codons,