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GLCNE Polyclonal Antibody, 100ul Bio-Reaction Tube This gene contains CAG trinucleotide

SKU: 92018095395

4.6
PLN141.00 PLN184.00

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GLCNE Polyclonal Antibody, 100ul Bio-Reaction Tube This gene contains CAG trinucleotideThe glucosamine (UDP N acetyl) 2 epimerase N acetylmannosamine kinase encoded by GNE is a bifunctional enzyme that initiates and regulates the biosynthesis of N acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction.

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Description

This gene contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues

AQP4 encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells

Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors

Expression is localized to proliferating fetal fibroblasts and the developing dermal layer

Yeast two-hybrid studies found ULK1/2 associated with modulators of the endocytic pathway

GLCNE Polyclonal Antibody, 100ul Bio-Reaction Tube This gene contains CAG trinucleotideThe glucosamine (UDP N acetyl) 2 epimerase N acetylmannosamine kinase encoded by GNE is a bifunctional enzyme that initiates and regulates the biosynthesis of N acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction.

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