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AIRE-1 Polyclonal Antibody, 100ul[BT-AP00311] Filtration This gene is a member

SKU: 91984809003

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AIRE-1 Polyclonal Antibody, 100ul[BT-AP00311] Filtration This gene is a memberAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and

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Description

This gene is a member of the PRAME (preferentially expressed antigen of melanoma) gene family which is expressed in many cancers but may function in reproductive tissues during development

In quiescent G0 phase cells

and this enhancement can be increased further in the presence of other androgen receptor associated coregulators

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U6 snRNA-specific) encodes a nucleotidyl transferase that functions as both a terminal uridylyltransferase and a nuclear poly (A) polymerase

AIRE-1 Polyclonal Antibody, 100ul[BT-AP00311] Filtration This gene is a memberAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and

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