Caspase-8 Polyclonal Antibody, 100ul[BT-AP14674] Cell Dissociation Alternative splicing occurs at TNS2

Alternative splicing occurs at TNS2 and three transcript variants encoding three distinct isoforms have been identified

The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17

Mutations in this gene have been found in patients with velocardiofacial syndrome

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and suicidality

Caspase-8 Polyclonal Antibody, 100ul[BT-AP14674] Cell Dissociation Alternative splicing occurs at TNS2This gene encodes a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large