FRS2(Phospho Tyr436) Polyclonal Antibody, 50ul Adeno-associated Virus Packaging The protein encoded by this

The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate

May be involved in apoptosis signaling in the presence of the reinoid CD437

A pseudogene of this gene is located on the long arm of chromosome 7

This gene is implicated in B cell development and lymphomagenesis

Interacts directly with BNIP1/SEC20L and ZW10

FRS2(Phospho Tyr436) Polyclonal Antibody, 50ul Adeno-associated Virus Packaging The protein encoded by thisAdapter protein that links FGR and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.,PTM: Phosphorylated on tyrosine residues upon stimulation by NGF.,PTM: Ubiquitinated when tyrosine phosphorylated and in a complex with GRB2. The unphosphorylated form is not subject to ubiquitination.,sequence Translated as stop.,Contains 1 IRS type