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FGD4 Rabbit Polyclonal Antibody, 100ul Transporters A suggested role for the

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FGD4 Rabbit Polyclonal Antibody, 100ul Transporters A suggested role for theThis gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament binding domain which together with its Dbl homology domain and one of its pleckstrin homology domains can form microspikes. This protein can activate MAPK8 independently of the actin filament binding domain and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The

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Description

A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA

It responds to changes in the cellular environment and represses pol III transcription

fluorescence

Activity of this gene has been associated with human cancer

Mice lacking this gene contain misplaced neurons (heterotopia) in some regions of the brain| possibly from defects in neuronal migration

FGD4 Rabbit Polyclonal Antibody, 100ul Transporters A suggested role for theThis gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament binding domain which together with its Dbl homology domain and one of its pleckstrin homology domains can form microspikes. This protein can activate MAPK8 independently of the actin filament binding domain and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The

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