NEK1 Polyclonal Antibody, 50ul Yeast Expression Four alternatively spliced transcript variants

Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene

Elongator complex protein 2 encoded by ELP2 is a core subunit of the elongator complex

like all members of the GPCR superfamily

is expressed in a variety of tissues with the highest levels in heart and pancreas

This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer

NEK1 Polyclonal Antibody, 50ul Yeast Expression Four alternatively spliced transcript variantsThe protein encoded by this gene is a serine threonine kinase involved in cell cycle regulation. The encoded protein is found in a centrosomal complex with FEZ1, a neuronal protein that plays a role in axonal development. Defects in this gene are a cause of polycystic kidney disease (PKD). Several transcript variants encoding different isoforms have been found for this gene.