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ZIC5 Rabbit Polyclonal Antibody, 50ul Peptide Synthesis Alternative splicing yields two isoforms

SKU: 89877116135

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ZIC5 Rabbit Polyclonal Antibody, 50ul Peptide Synthesis Alternative splicing yields two isoforms

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Description

Alternative splicing yields two isoforms that differ in abundance and expression patterns

Naturally occuring readthrough transcription occurs between this locus and the downstream GNMT (glycine N-methyltransferase) gene and is represented with GeneID:107080644

one encoding a secreted isoform and the others encoding nonsecreted isoforms

CDKL3 was identified as a gene absent in leukemic patients with chromosome 5q deletion

The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases| suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery

ZIC5 Rabbit Polyclonal Antibody, 50ul Peptide Synthesis Alternative splicing yields two isoforms

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