NBPF6 Polyclonal Antibody, 50ul NGS Oligos resulting in five different isoforms

resulting in five different isoforms with distinct properties

sequence-specific DNA binding and transcriptional activator activity

The encoded protein is involved in RNA transcription by RNA polymerase II and nucleotide excision repair and associates with the Cdk-activating kinase complex

associates with endocytic vesicles

Some of these isoforms may undergo similar processing to generate the mature peptide

NBPF6 Polyclonal Antibody, 50ul NGS Oligos resulting in five different isoformsThis gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number