TTF2 Polyclonal Antibody, 100ul Biomatrix Increased expression of this gene

Increased expression of this gene has been reported in a variety of tumor types

It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA

Phosphorylated by ATR upon DNA damage

May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death

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TTF2 Polyclonal Antibody, 100ul Biomatrix Increased expression of this geneThis gene encodes a member of the SWI2 SNF2 family of proteins, which play a critical role in altering protein DNA interactions. The encoded protein has been shown to have dsDNA dependent ATPase activity and RNA polymerase II termination activity. This protein interacts with cell division cycle 5 like, associates with human splicing complexes, and plays a role in pre mRNA splicing.